L-Aspartic acid

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

天冬氨酸是人体的非必需氨基酸，天冬氨酸整体带负电荷，在其他氨基酸的合成以及柠檬酸和尿素循环中发挥着重要作用。

Aspartic Acid is a non-essential amino acid in humans, Aspartic Acid has an overall negative charge and plays an important role in the synthesis of other amino acids and in the citric acid and urea cycles. Asparagine, arginine, lysine, methionine, isoleucine, and some nucleotides are synthesized from aspartic acid. Aspartic acid also serves as a neurotransmitter.(In Vitro):L-Aspartic acid is shown to be a suitable prodrug for colon-specific drug deliverly. L-[3H]Asp remaining in the brain at 5 min is increased by 206 and 178% by preadministration of 100 mM L-Aspartic acid and 100 mM L-Glu, respectively, whereas 100 mM D-Asp does not affect L-[3H]Asp efflux transport. That value for L-[3H]Glu at 20 min is increased by 145 and 156% by coadministration with 100 mM L-Aspartic acid and 100 mM L-Glu, respectively, but not by D-Asp. It is interesting that the apparent efflux rate of L-Aspartic acid across the BBB is sevenfold faster than that of L-Glu.

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L-Aspartic acid is shown to be a suitable prodrug for colon-specific drug deliverly. L-[3H]Asp remaining in the brain at 5 min is increased by 206 and 178% by preadministration of 100 mM L-Aspartic acid and 100 mM L-Glu, respectively, whereas 100 mM D-Asp does not affect L-[3H]Asp efflux transport. That value for L-[3H]Glu at 20 min is increased by 145 and 156% by coadministration with 100 mM L-Aspartic acid and 100 mM L-Glu, respectively, but not by D-Asp. It is interesting that the apparent efflux rate of L-Aspartic acid across the BBB is sevenfold faster than that of L-Glu.

Aspartic acid | Aspatofort | EC 200-291-6

Others

Other Targets

Others

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56-84-8

133.1

C4H7NO4

>98% (HPLC)

H2O : 8.33 mg/mL 62.58 mM

C(C(C(=O)O)N)C(=O)O

L-aspartic acid

(-20℃)

With Ice Pack

≥ 2 years