
L-Aspartic acid
CAS No. 56-84-8
L-Aspartic acid ( Aspartic acid | Aspatofort | EC 200-291-6 )
产品货号. M18824 CAS No. 56-84-8
天冬氨酸是人体的非必需氨基酸,天冬氨酸整体带负电荷,在其他氨基酸的合成以及柠檬酸和尿素循环中发挥着重要作用。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
500MG | ¥332 | 有现货 |
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1G | ¥389 | 有现货 |
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生物学信息
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产品名称L-Aspartic acid
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述天冬氨酸是人体的非必需氨基酸,天冬氨酸整体带负电荷,在其他氨基酸的合成以及柠檬酸和尿素循环中发挥着重要作用。
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产品描述Aspartic Acid is a non-essential amino acid in humans, Aspartic Acid has an overall negative charge and plays an important role in the synthesis of other amino acids and in the citric acid and urea cycles. Asparagine, arginine, lysine, methionine, isoleucine, and some nucleotides are synthesized from aspartic acid. Aspartic acid also serves as a neurotransmitter.(In Vitro):L-Aspartic acid is shown to be a suitable prodrug for colon-specific drug deliverly. L-[3H]Asp remaining in the brain at 5 min is increased by 206 and 178% by preadministration of 100 mM L-Aspartic acid and 100 mM L-Glu, respectively, whereas 100 mM D-Asp does not affect L-[3H]Asp efflux transport. That value for L-[3H]Glu at 20 min is increased by 145 and 156% by coadministration with 100 mM L-Aspartic acid and 100 mM L-Glu, respectively, but not by D-Asp. It is interesting that the apparent efflux rate of L-Aspartic acid across the BBB is sevenfold faster than that of L-Glu.
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体外实验——
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体内实验L-Aspartic acid is shown to be a suitable prodrug for colon-specific drug deliverly. L-[3H]Asp remaining in the brain at 5 min is increased by 206 and 178% by preadministration of 100 mM L-Aspartic acid and 100 mM L-Glu, respectively, whereas 100 mM D-Asp does not affect L-[3H]Asp efflux transport. That value for L-[3H]Glu at 20 min is increased by 145 and 156% by coadministration with 100 mM L-Aspartic acid and 100 mM L-Glu, respectively, but not by D-Asp. It is interesting that the apparent efflux rate of L-Aspartic acid across the BBB is sevenfold faster than that of L-Glu.
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同义词Aspartic acid | Aspatofort | EC 200-291-6
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number56-84-8
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分子量133.1
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分子式C4H7NO4
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纯度>98% (HPLC)
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溶解度H2O : 8.33 mg/mL 62.58 mM
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SMILESC(C(C(=O)O)N)C(=O)O
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化学全称L-aspartic acid
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Leopold CS, et al. In vivo pharmacokinetic study for the assessment of poly(L-aspartic acid) as a drug carrier for colon-specific drug delivery. J Pharmacokinet Biopharm. 1995 Aug;23(4):397-406.
产品手册




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